Living organisms are continuously exposed to a myriad of DNA damaging agents that can impact health and modulate disease-states. However, robust DNA repair and damage-bypass …

Sep 8, 2023 · DNA Damage and DNA Repair To overcome the harmful effects of DNA damage, cells have various systems such as DNA repair mechanisms, damage tolerance pathways, cell …

Mar 17, 2025 · DNA end resection is crucial for most DNA double-strand break repair pathways. This Review discusses the molecular mechanisms of end resection and its regulation, focusing …

The page provides an extensive overview of DNA mutations and repair mechanisms, aimed at biochemistry majors. It covers types and causes of DNA mutations, mechanisms of DNA …

Jan 16, 2024 · DNA damage is a critical factor contributing to genetic alterations, directly affecting human health, including developing diseases such as cancer and age-related disorders. DNA …

Direct Reversal of Base Damage Direct reversal of DNA damage is a mechanism of repair that does not require template and is applied to two main types of damage. Perhaps the most …

DNA damage resulting in multiple broken chromosomes DNA repair is a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome. …

Explore the intricacies of DNA damage and the sophisticated repair mechanisms that maintain genetic integrity.

In addition to blocking cell cycle progression, DNA damage sensors also activate DNA repair mechanisms that are specific for the type of damage present. For example, single stranded …

DNA has many elaborate mechanisms to repair any damage or distortion. The most frequent sources of damage to DNA are the inaccuracy in DNA replication and chemical changes in …